A new study has raised concerns about the long-term use of antidepressant medications, suggesting that their benefits may be more limited than previously believed.
Researchers are also warning about potential health risks and severe withdrawal symptoms associated with prolonged use.
More than 330 million people worldwide are living with depression, and a significant number of them take antidepressant medications on a daily basis.
Studies show that antidepressant use is nearly twice as common among women as it is among men.
In high-income countries such as the United States, the United Kingdom, and Australia, many patients continue taking these medications for extended periods, often for years.
According to emerging scientific evidence, commonly prescribed antidepressants may not work by correcting a fundamental deficiency of serotonin, a chemical messenger in the brain, as was long believed.
Researchers say growing evidence is challenging earlier theories about how these medications produce their effects.
The findings have renewed debate within the medical community about the long-term effectiveness of antidepressant treatment.
Concerns over withdrawal symptoms
Researchers have also warned that long-term antidepressant use can lead to severe and distressing withdrawal symptoms when patients stop taking the medication.
In some cases, these symptoms may be more serious and prolonged than previously expected, making it difficult for patients to discontinue treatment.
Experts stress that patients should never stop taking antidepressants abruptly without consulting their healthcare provider.
In light of the findings, researchers are urging healthcare professionals to reassess patients' treatment plans regularly.
They recommend that doctors review antidepressant use at least once every six months to determine whether continued treatment remains necessary and beneficial.
Experts believe regular evaluations could help balance the potential benefits of treatment against any emerging risks.
